How to use neem tree for abortion

Induced termination of pregnancy by purified extracts of Azadirachta Indica (Neem): mechanisms involved

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. 1997 Jun;37(6):485-91.

doi: 10.1111/j.1600-0897.1997.tb00264.x.

G P Talwar  1 , S Shah, S Mukherjee, R Chabra



  • 1 International Centre for Genetic Engineering and Biotechnology, Aruna Asaf Ali Marg, New Delhi, India.
  • PMID: 9228306
  • DOI: 10.1111/j.1600-0897.1997.tb00264.x

G P Talwar et al. Am J Reprod Immunol. 1997 Jun.

. 1997 Jun;37(6):485-91.

doi: 10. 1111/j.1600-0897.1997.tb00264.x.


G P Talwar  1 , S Shah, S Mukherjee, R Chabra


  • 1 International Centre for Genetic Engineering and Biotechnology, Aruna Asaf Ali Marg, New Delhi, India.
  • PMID: 9228306
  • DOI: 10.1111/j.1600-0897.1997.tb00264.x


Problem: To develop a self-administered, orally delivered method for abrogation of early pregnancy.

Method: Use of purified Neem extracts containing immunomodulators stimulating Th2 cells and macrophages; test animals, rats, baboons, and monkeys, onset of pregnancy confirmed by surgery and counting of implants on day 7 in rats and by chorionic gonadotropin (CG) and progesterone assays in primates; termination defined by complete resorption on day 15 in rats and by bleeding and decline of CG and progesterone in baboons.

Results: Pregnancy was terminated successfully in both rodents and primates with no significant side effects. Fertility was regained in both species after one or two irregular cycles. Progeny born had normal developmental landmarks and mothered normal litters in the course of time. The active principle in Neem has been partially fractionated by activity-guided purification. A cascade of events are involved in abrogation of pregnancy. In primates, a decrease in progesterone is an early event. A transient increase in CD4 and CD8 cells is noted in spleen at 96 hr and in mostly CD8 cells in mesenteric lymph nodes. Treatment causes an elevation of both immunoreactive and bioactive TNF-alpha and gamma-interferon in serum, mesenteric lymph nodes, and foetoplacental tissue.

Conclusion: Immunomodulators of plant origin are potentially usable for termination of unwanted pregnancy

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Plant immunomodulators for termination of unwanted pregnancy and for contraception and reproductive health

. 1997 Apr;75(2):190-2.

doi: 10.1038/icb. 1997.27.

G P Talwar  1 , P Raghuvanshi, R Misra, S Mukherjee, S Shah



  • 1 Reproductive Health and Vaccinology Division, International Centre for Genetic Engineering and Biotechnology, Aruna Asaf Ali Marg, New Delhi, India.
  • PMID: 9107574
  • DOI: 10.1038/icb.1997.27

G P Talwar et al. Immunol Cell Biol. 1997 Apr.

. 1997 Apr;75(2):190-2.

doi: 10.1038/icb.1997. 27.


G P Talwar  1 , P Raghuvanshi, R Misra, S Mukherjee, S Shah


  • 1 Reproductive Health and Vaccinology Division, International Centre for Genetic Engineering and Biotechnology, Aruna Asaf Ali Marg, New Delhi, India.
  • PMID: 9107574
  • DOI: 10.1038/icb.1997.27


Neem (Azadirachta indica) seed and leaf extracts have spermicidal, anti-microbial, anti-fungal and anti-viral properties. They are also immunomodulators that induce primarily a Th2 type response. These properties are being exploited to develop two different useful methods of fertility control. Neem extracts given orally at early post-implantation stage terminate pregnancy in rodents and primates. Treatment has no residual permanent effect and fertility is regained in subsequent cycles. The mechanism by which the action occurs is not fully clear. A transient increase in CD4 and more significantly in CD8 cells is noticed in mesenteric lymph nodes and spleen. A rise in immunoreactive and bioactive TNF-alpha and IFN-gamma in draining lymph nodes, serum and foetal-placental tissue is observed. A polyherbal cream and pessary have been developed containing three active ingredients of plant origin. These have synergistic spermicidal properties on human sperm as determined by the Sander Cramer test. Their use before mating has high contraceptive efficacy in rabbits and baboons. Another interesting property is their inhibitory action on a wide spectrum of micro-organisms, including Candida albicans, C. tropicalis, Neisseria gonorrhoeae, the multidrug-resistant Staphylococcus aureus and urinary tract Escherichia coli, Herpes simplex-2 and HIV-1. Phase I clinical trials have been completed in India, Egypt and the Dominican Republic, and indicate the safety of the formulation, its acceptability and beneficial action invaginosis due to infections.

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  • Induced termination of pregnancy by purified extracts of Azadirachta Indica (Neem): mechanisms involved.

    Talwar GP, Shah S, Mukherjee S, Chabra R. Talwar GP, et al. Am J Reprod Immunol. 1997 Jun;37(6):485-91. doi: 10.1111/j.1600-0897.1997.tb00264.x. Am J Reprod Immunol. 1997. PMID: 9228306

  • Early post implantation contraceptive effects of a purified fraction of neem (Azadirachta indica) seeds, given orally in rats: possible mechanisms involved.

    Mukherjee S, Garg S, Talwar GP. Mukherjee S, et al. J Ethnopharmacol. 1999 Nov 30;67(3):287-96. doi: 10.1016/s0378-8741(99)00068-9. J Ethnopharmacol. 1999. PMID: 10617063

  • Spermicidal & contraceptive properties of Praneem polyherbal pessary.

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  • [Current status of the female condom in Africa].

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Neem leaves - useful properties


  1. Neem leaves - what is it?
  2. How does the Neem tree grow?
  3. What is made from Indian lilac?
  4. Essential Benefits of Neem Leaves
  5. Neem leaves in cosmetology, against influenza, infections and fungus
  6. Neem leaves - application
  7. What is neem leaf tea and how to make it?
  8. Neem flower petals
  9. Neem Fruit Oil
  10. Where to buy neem leaves and how to store them properly?
  11. Neem leaves: contraindications and side effects

Before you buy neem leaves in St. Petersburg, check out this article, where you will learn about the most studied medicinal plant in the world of Ayurveda - the beaded tree or Indian lilac, which is common under the name Neem. This tree is the only one that has hosted eight worldwide scientific conferences. The first one took place at 1980 in Germany, the last - in 2007 in India. Others took place in Canada, Australia, Kenya. Why is azadirachta indica of such interest to scientists and pharmacists?

Neem leaves - what is it?

Neem or Azadirachta indica (Indian lilac) is an evergreen tree that belongs to the meliaceae (redwood) family and is found throughout the world. In different countries and cultures, it has its own names, for example, Antelaea azadirachta, Arishta, Arishtha, Beaded tree, holy tree, Huile de Neem, Margosa, Margousier, Melia azadirachta, Neem Tree, Nim, Nimb, nimba, Persian - lilac pride China, Al-Shurish.

Neem is a large tree, about 25 meters tall with a fairly straight trunk. A flowering plant that begins to bear fruit in three to five years. The bark of this tree is gray and rough. The leaves are up to 30 centimeters long. Each leaf has 10-12 teeth, which are 7 centimeters long and 2.5 centimeters wide. All parts of the selected plant are used as a medicine for the treatment of many diseases and ailments.

How does the Neem tree grow?

Neem, in comparison with other species of its family, adapts well to environmental conditions. Due to its water-retaining capacity, large-scale neem plantation helps fight desertification, deforestation, and soil erosion. Arishta has a high rate of photosynthesis and releases more oxygen than other tree species.

Neem withstands temperature differences of approximately 10°C in both directions. In areas with low rainfall and high wind speeds, neem is useful as a windbreak. Nima plantations have been used to stop the spread of the Sahara desert into Somalia and Mauritania.

A mature neem tree yields about 10 crops - this is 100 tons of dry biomass per 1 ha. The biomass consists of leaves (50%), fruits (25% each) and wood (25% each). Nim is used as a water purifier. So the powder from the leaves of Neem is used as a sorbent to remove dyes from water.

What is made from Indian lilac?

Oil and cake are made from seeds. The oil is used as a medicine. It anesthetizes, has anticholinergic, anthelmintic, antihistamine, antiprotozoal, antipyretic, antiviral, bactericidal properties. Produced in different forms:

  • cosmetics,

  • hair oil

  • lubricants and ointments,

  • shampoos,

  • soap,

  • toothpastes.

From the branches produce a deodorant for the oral cavity, toothache blockers. Also, the bark comes into play. The flowers are used in the manufacture of analgesics, curries, nectars, soaps and stimulants. Technologies for the production of glue, honey, resins also include the components of this plant.

Main health benefits of Neem leaves

There are over 130 different biologically active compounds in the neem leaf! No wonder it is such an effective antiviral and antibacterial agent, as well as a powerful immune stimulant. Huile de Neem destroys the bacteria that cause infections, stimulates the immune system and promotes a speedy recovery.

Nim is traditionally used to treat fever and diabetes. Several active chemical compounds are present in the selected plant:

  • glycosides,

  • dihydrochalcone,

  • coumarin,

  • tannins,

  • azadirachtin,

  • nimbin,

  • nimbidin,

  • diterpenoids,

  • triterpenoids,

  • proteins,

  • carbohydrates,

  • sulfur compounds,

  • polyphenols, etc.

Murli Manohar, author of Ayurveda for All, points out that they purify the blood, prevent damage caused by free radicals in the body, remove toxins, and treat insect bites and ulcers. They have antibacterial properties, help with burns and any skin problems.

Neem leaves in cosmetology, against influenza, infections and fungus

Neem leaf is known in Ayurvedic texts for being an indispensable remedy for skin diseases. It works as an antifungal, antiseptic, and anti-inflammatory agent. Effective in the treatment of eczema, ringworm and acne. Traditional manufacturing methods involve grinding the leaves into a paste and then applying it directly to wounds and ulcers. It is nourishing for hair.

In India, people sprinkle fresh Neem leaf near the beds of flu or fever patients and hang a bunch of leaves on the door outside. This cleans the air of viruses and bacteria, which in turn helps to disinfect the room and prevent the spread of the disease. For example, azadirachtin exhibits antifungal properties, preventing the formation of unwanted spore bacteria.

Neem Leaves - Application

The most valuable thing in this plant is contained in the leaf. It has antidermal, antifungal, antifungal, antituberculous, antitumor, antiseptic, antiviral, contraceptive, cosmetic properties. They are even added to mineral fertilizers. Here are some ways to use neem leaves.

  • Wound healing: Make a paste of neem leaves and apply it on your wounds or insect bites. Apply several times a day until it heals.

  • Dandruff treatment : Boil a bunch of neem leaves until the water turns green, let it cool. After shampooing your hair, clean it with this water.

  • Inflammation of the eyes : boil a few neem leaves, cool the water, and then wash your eyes with the infusion. So irritation, fatigue or redness will go away.

  • For acne and pimples : Grind a few leaves, make a paste and apply daily until the pimples are dry. The paste also helps with any rashes, dark spots and chronic ulcers.

  • Ear diseases : Mix some neem leaves and add some honey to it. Use a few drops of this mixture to treat any ear boils.

  • Skin diseases : Turmeric combined with leaf paste helps in the treatment of itching, eczema, ringworms and some mild skin conditions.

  • Immunity : grind and steep in a glass of water.

What is neem leaf tea and how to make it?

Neem tea is usually served hot. About 1 teaspoon should be used per 1 cup. You need to soak for 5-10 minutes. It can also be refrigerated and served cold. Buy neem leaves and mix them with black or green tea or herbs and spices like cinnamon. Blending tea with sweet and spicy flavors helps to balance the bitterness of the leaves.

You can make your own mixture by adding ingredients such as cardamom, fennel, orange peel. The bitterness is well compensated by adding honey or sugar and lemon juice to freshly brewed neem tea. The leaves are often sold as a fine powder. A small amount of powder should be mixed in warm or cool water and mixed well before use. But it is important not to overdose. Read about it on the package.

Neem flower petals

Most parts of the tree are bitter, with the exception of its flowers. Huile de Neem flowers are pale white with a hint of a sweet jasmine scent. These flowers can be used fresh, dried or powdered. In cooking, they are added to dishes such as flower rice, pachadi, rasam, lentils, and more. Dry fried sprinkled on top of the dish. You can just decorate the dish with them.

Pharmacists know that flowers are prescribed to treat anorexia, nausea, belching and intestinal worms. A 2008 study also found Neem flower extract to be an effective contraceptive. It is noteworthy that the British adopted the habit of brushing their teeth from the Indians, simply using the branches as chewing gum. It fights germs, keeps your saliva alkaline, treats swollen gums, and whitens your teeth.

Fruit oil

Neem oil, which is extracted from its fruit, is added as an ingredient in cosmetics and other beauty products: soaps, hair oils, tonics, soap solutions, etc. This oil can treat a bunch of skin conditions and is known to repel mosquitoes. . The solution can be mixed with coconut oil and applied to your body. Here are some indications for prescribing neem oil:

  • For acne: dilute 2-3 drops of oil in water. Apply cotton wool soaked in the solution to the affected areas. Carry out the procedure regularly.

  • Anti-Age: Neem oil helps fight aging skin and relieve skin irritation and itching.

  • For hair growth on the head: rub a small amount of the consistency on the scalp, leave it for 5-10 minutes and rinse. Neem oil will strengthen your hair, prevent hair loss. Easily copes with dandruff.

Where to buy Neem leaves and how to store them properly?

Neem can be found in health food stores, organic specialty stores and online. They should be stored in an airtight container in a dry, dark, cool place. So the leaves of the neem do not deteriorate, do not become stale. We recommend using them within six months of purchase. In finished form, for example, in paste, tea, ointments, infusions - you need to apply immediately within a week. Most importantly, follow the recommendations that are given on the product packaging.

Neem leaves: contraindications and side effects

The use of neem is not recommended for pregnant women, breastfeeding women, couples who want to become pregnant, children, people taking lithium, people with autoimmune disorders, or diabetes. It also shouldn't be used in an organ transplant or someone with an operation scheduled within two weeks.

Indications for children: Children should not take neem seeds or oil by mouth. The reaction includes serious side effects:

  1. Pregnancy and lactation: Neem oil and bark are contraindicated during pregnancy. They can cause miscarriage. There are practically no studies on pregnancy and breastfeeding. Therefore, it is better not to take risks.
  2. Individuals with autoimmune diseases: Conditions such as multiple sclerosis (MS), lupus erythematosus (systemic lupus erythematosus, SLE), rheumatoid arthritis (RA) have autoimmune mechanisms. If you take Neem leaves, then the immune system will become more aggressive.
  3. Diabetes: there is evidence that neem lowers blood sugar levels, which exacerbates diabetes. In any case, it is better to consult a doctor.
  4. Infertility: Neem has been observed to affect reproductive function in men. If you are trying to have children, avoid using this herb.
  5. Organ Transplant : Some reports indicate that Indian lilac may reduce the effectiveness of certain drugs used to prevent organ rejection. Also, you can not take it 2 weeks before the scheduled operation.

Pharmacological abortion in Surgut | Doctorplus Medical Center

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Pharmacological abortion in Surgut

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An innovative way to get rid of an unwanted pregnancy is pharmacological abortion. The procedure involves the use of special preparations that destroy the fetal egg. The advantage of manipulation is the absence of surgical intervention. It is advisable to carry out medical termination of pregnancy in its early stages.

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What is the essence of the procedure?

The procedure is based on the use of drugs whose active ingredient is mifepristone. Its main function is to block progesterone, which maintains the hormonal background of pregnancy. The substance directly acts on the fetus, destroying its membranes. As a result, the embryo exfoliates from the uterine walls and an abortion occurs. As additional measures, prostaglandins, which increase muscle spasm, can be used.

Method advantages

  • The effectiveness of the procedure is ninety-five percent.

  • Carrying out in the period up to six weeks of pregnancy is the key to a successful result.

  • The uterus and its cervix are not injured due to the lack of surgical intervention.

  • The procedure does not involve the use of anesthesia.

  • Virtually no complications.

  • Small risk of developing undesirable consequences compared with other existing methods of abortion.

Contraindications for the procedure

  • Allergic reaction to the drug.

  • SARS.

  • HIV.

  • Patient intolerance to the active substance.

  • Severe anemia.

  • Ectopic pregnancy.

  • AIDS.

  • Impaired kidney function with reduced filtration and reabsorption processes.

  • Chronic pathology of the excretory system.

  • Liver failure, occurring in acute or chronic forms.

  • More than six weeks pregnant.

  • If pregnancy occurs while using a device such as an intrauterine device.

  • Long-term treatment with corticosteroids.

  • Neoplasms in the uterus.

  • Diseases of the gastrointestinal tract.

  • Pathology of hemostasis.

  • Inflammatory gynecological diseases.

The pros and cons of recommending pharmacological abortion for at-risk patients should be weighed. These include:

  • Scars on the body of the uterus resulting from surgery.

  • Patients with hypertension.

  • Lactation period. During a medical abortion, you will have to stop breastfeeding for fourteen days.

  • Patients over thirty-five who smoke.

Algorithm of action after the procedure

Three days after the abortion with the use of medication, the patient must come to the doctor for an examination. An ultrasound examination of the pelvic organs is performed. If the doctor sees that the fetal egg has not completely come out, a plan for further measures will be developed. Another ultrasound is recommended to be carried out in the period from seven to fourteen days.

Pharmacological abortion is carried out strictly within the walls of a specialized medical institution by qualified specialists. After an abortion, it is necessary to decide on the method of contraception. Pharmacological abortion is strictly forbidden to be carried out independently, because manipulation is possible only under the supervision of a gynecologist with sufficient experience.

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